off-gas analysis for bioprocess optimization


Efficient process optimization with O2 in situ measurement

Technical Short Facts

  • Measuring principle Zirconium dioxide, Galvanic cell
  • Measuring range 0,1-25 Vol.%, 1-50 Vol.%, 0-100 Vol.% (others on request)
  • Drift < ± 2% value / year
  • Accuracy <0,2% FS (full scale) ± 3% value
  • Housing Aluminium (IP65), PA
  • Mechanical connections G 1¼”, GL 45, Tri-Clamp SMS38, hose connection 4-12 mm etc.
  • Temperature inside of the sensor unit 580°C 1076°F 3°C higher than process temperature 5.4°F higher than process temperature Don‘t use in explosive atmosphere
  • Output RS232, 4-20mA, Ethernet (with BACCom), USB

Oxygen is the essential element of life and its measurement resembles a central point in controlling biotechnological processes. Applying BPC-O2 gas analyzers oxygen concentrations can be measured in situ directly from the exhaust gas flow. In combination with a bioprocess software (such as BlueVIS) the BCP-O2 can be used to calculate essential respiration parameters as OUR (oxygen uptake rate) and RQ (respiratory quotient). The BCP-O2 can be connected to the exhaust vent of any type or scale of fermenter and bioreactor, allowing you to scale up using the same measurement technology at every step. All BCP-analyzers are available with aluminum (pilot to industrial scale use) or PA (lab scale) casings.

BCP-O2 – non-invasive measurement independent from flow and scale

  • in-situ gas analysis ➔ non-invasive measurement directly where it happens
  • flow and scale independent ➔ one type of analyzer (technology) type for all scales ➔ less variations and unpredictable influences
  • direct integration in gas pipelines behind the sterile barrier ➔ calibrate your analyzer at any time without the risk of contamination
  • pressure and temperature compensated automatically leading to high accuracy and process reliability
  • universal mounting opportunities for convenient integration on new or existing equipment
  • standardized data interfaces for simple connection to any process lead system (PLS)

Application areas

  • pharmaceutical industry
  • biogas plants
  • any type of fermentation processes
  • laboratory scale
  • large industrial plants
  • (parallel) bioreactors
  • connection to single-use reactors available

BCP-O2, zirconium dioxide, suitable for 0,1-25 Vol.% and 1-50Vol.%

BCP-O2ec, galvanic cell, suitable for 0-100 Vol.%

Don't waste budget and "Use what you have"

Before you go and buy something new: check your lab! It might be enough to just buy several new components. We can show you how to turn your older equipment into a modern, fully equipped and controlled system.

Go and check your lab cabinets for 

  • an (older) culture vessel, bioreactor or fermenter
  • pH, pO2 probes
  • agitator control
  • digital mass flow controller or flow meter
  • pumps for feed addition and pH control
  • open software BlueVis 4.0
  • off-gas analyzers suitable for your application

Do you already have some of these items? — Perfect! With open bioprocess software BlueVIS we will connect all components and make your system run. Various communication protocols already have been integrated in BlueVIS. If yours is not supported yet, we will realize it.

Use what you have — Think sustainable and keep your invest low

  • Don't waste money on installation fees or trainings
  • Use equipment from manufacturers that you want to and not that you're told to
  • BlueVIS 4.0 is compatible with other process-control software via OPC

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Benefit from continuous off-gas data

See what´s happening when it´s happening. MS and off-gass analyzers - it doesn´t have to be either or but can also be complementary. Read here why and how to benefit from continuous off gas measurement made by BlueSens although you already might have a mass spec.

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OEM sensors – customized sensors are our daily business

BlueSens' high quality measurement technique integrated in your device or provided with your label? We are already producing our sensors OEM for market leading fermenter manufacturers.

If you are interested in an individual OEM solution, please

Contact us