BlueInOne Cell

Real time combined CO2/O2 gas analyzer for cell culture processes

Technical Short Facts

  • Concentration ranges: CO2: 0 - 10 Vol.%, O2: 0 - 100 Vol.% or CO2: 0 - 25 Vol.%, O2: 0 - 100 Vol.% (others available on request)
  • Measuring principle infrared IR(CO2), galvanic cell (O2)
  • Temperature inside of the sensor unit: 3°C / 5.4°F higher than process temperature
  • various opportunities for mechanical connection (eg 4, 6, 8, 10, 12mm outer diameter, 4,6,8mm inner diameter, ¼”, 1/8” , 1 ¼”, ¼” and ½” swagelok, TriClamp)
  • electronic output: active output, maximum 500 Ohm at 24V power supply, RS232, RS485 Modbus, 2x 4-20mA, USB, Modbus OPC server (with BlueVis)
  • optional display available

BlueInOne Cell has been designed to measure concentrations of carbon dioxide and oxygen in biotechnological cell culture processes. It can be integrated in the exhaust gas flow of the bioprocess and measures the gas concentrations online and in real-time. Sitting behind the sterile barrier the analyzer can be calibrated at any time with no risk of contaminating the culture. Fluctuations of pressure and humidity are automatically compensated. BlueInOne fits on every fermenter from benchtop to industrial scale.

BlueInOne Cell - understanding bioprocesses

  • parallel measurement of O2 and CO2 ➔ no need for sampling
  • different CO2 and O2 calibration ranges available
  • will operate from 0 to 100% oxygen
  • compact stainless steel housing ➔ robust and easy to clean
  • PAT and QbD conforming in-situ-measurement ➔ for highest standard of quality
  • auto compensated for humidity and pressure ➔ no need for extra gas coolers, pumps or valves
  • real-time process optimization ➔ see what happens when it happens – fast response options

Application areas

  • Cell Culture, Cell growth processes
  • Microbial cultivations with anaerobic phase or containing volatile hydrocarbon
  • Online fermentation monitoring
  • From lab to industrial scale

Keep an eye on your data

For all BlueInOne gas analyzers there is a convenient additional display available. Measured data is shown in real-time. The display is connected via data cable (up to 5 meters long) to the analogue 4-20mA output of the BlueInOne analyzer without blocking any ports. Magnets on the rear of the housing of the display make mounting easy and convenient. In addition, the display includes a button for performance of the 1-point calibration.

  • Convenient: the current measured values directly on site in view
  • Easy installation: quick control without software
  • Flexible to install, easy mounting
  • Time savings: start the one-point calibration easily even if the BlueInOne is hard to reach
  • 4-20 mA port included, no ports are blocked
  • Variants for all BlueInOne available

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BlueVary consists of a basis element with measurement places for two of the variable gas sensor cartridges. That way two gases can be measured in parallel. The third place holds a sensor cartridge for pressure and/or humidity. An integrated display ensures insight of the measured data at any time. Various mechanical connections make BlueVary fit on every fermenter. Numerous data output possibilities are available. Annual maintenance is unnecessary. To maintain accuracy of the readings a one-point calibration has to be performed (by the user) in reasonable time intervals.

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OEM sensors – customized sensors are our daily business

BlueSens' high quality measurement technique integrated in your device or provided with your label? We are already producing our sensors OEM for market leading fermenter manufacturers.

If you are interested in an individual OEM solution, please

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