Struggling with high Lactate level in your CHOs? Have a look on initial glucose and use a BlueSens off-gas analyzer
What impact does the initial glucose concentration have on metabolic activity on a CHO cell culture? In this work of the Hamburg University of Technology, Institute of Bioprocess- and Biosystems Engineering Germany and Cell Service Center, Hamburg University of Technology BlueSens' BlueVary off-gas analyzer was used to deliver reliable measurements for calculation of specific oxygen uptake rate (qOUR) and specific lactate uptake rate (qLac) as indicators. The results are more than interesting, but have a look yourself.